Epilepsy in adult patients with tuberous sclerosis complex
نویسندگان
چکیده
منابع مشابه
Current management for epilepsy in tuberous sclerosis complex.
PURPOSE OF REVIEW This article reviews the most significant advances in the field of epilepsy associated with tuberous sclerosis complex, with emphasis on new advances in the knowledge of the pathophysiological mechanisms of epileptogenicity, progress in identifying the epileptogenic zone, and the rationale for surgical management in individuals with intractable seizures. RECENT FINDINGS Adva...
متن کاملThe natural history of epilepsy in tuberous sclerosis complex.
BACKGROUND Although epilepsy affects most patients with tuberous sclerosis complex (TSC), little is known about the natural history of epilepsy in this genetic disease. METHODS A retrospective chart review of all patients with TSC seen between January 2002 and October 2008. Charts were reviewed for a history of infantile spasms (IS), seizure other than IS, refractory epilepsy, Lennox-Gastaut ...
متن کاملDevelopmental outcome of epilepsy surgery in tuberous sclerosis complex.
In Tuberous sclerosis complex (TSC), neurological dysfunction, usually in association with epilepsy, is responsible for the greatest degree of disease-related disability. Epilepsy surgery is increasingly recognized as a therapeutic option given the often medication-resistant nature of the disease. Seven subjects with medically refractory epilepsy associated with TSC, who underwent surgery at a ...
متن کاملCharacteristics and the clinical prognosis of epilepsy in patients with a diagnosis of tuberous sclerosis complex
Ad dress for Cor res pon den ce: Elif Yüksel Karatoprak MD., Medeniyet University, Göztepe Education and Research Hospital, Pediatric Neurology Clinic, İstanbul, Turkey E-mail: [email protected] Re cei ved: 08.09.2012 Ac cep ted: 12.27.2012 Turkish Archives of Pediatrics, published by Galenos Publishing Characteristics and the clinical prognosis of epilepsy in patients with a diagnosis o...
متن کاملNovel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex
Tuberous Sclerosis Complex (TSC) is a genetic hamartoma syndrome frequently associated with severe intractable epilepsy. In some TSC patients epilepsy surgery is a promising treatment option provided that the epileptogenic zone can be precisely delineated. TSC brain lesions (cortical tubers) contain dysmorphic neurons, brightly eosinophilic giant cells and white matter alterations in various pr...
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ژورنال
عنوان ژورنال: Acta Neurologica Scandinavica
سال: 2021
ISSN: 0001-6314,1600-0404
DOI: 10.1111/ane.13416